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Talal A Chatila Selected Research

X-Linked Syndrome Enteropathy Polyendocrinopathy Immune Dysregulation

1/2021Single-cell analysis of FOXP3 deficiencies in humans and mice unmasks intrinsic and extrinsic CD4+ T cell perturbations.
1/2015Regulatory T-cell deficiency and immune dysregulation, polyendocrinopathy, enteropathy, X-linked-like disorder caused by loss-of-function mutations in LRBA.
7/2007FOXP3 is a homo-oligomer and a component of a supramolecular regulatory complex disabled in the human XLAAD/IPEX autoimmune disease.

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Talal A Chatila Research Topics

Disease

15Inflammation (Inflammations)
05/2022 - 10/2003
14Food Hypersensitivity (Food Allergy)
12/2020 - 01/2013
8Asthma (Bronchial Asthma)
11/2022 - 10/2004
6Infections
01/2022 - 12/2005
6Eosinophilia
01/2022 - 10/2003
6Hypersensitivity (Allergy)
01/2017 - 10/2004
5Anaphylaxis (Anaphylactic Shock)
10/2016 - 03/2011
5Virus Diseases (Viral Diseases)
08/2015 - 12/2009
4Dysbiosis
10/2019 - 08/2015
4Colitis
11/2017 - 12/2012
4Autoimmune Diseases (Autoimmune Disease)
01/2016 - 11/2005
3Candidiasis (Moniliasis)
01/2021 - 11/2016
3X-Linked Syndrome Enteropathy Polyendocrinopathy Immune Dysregulation
01/2021 - 07/2007
3Job Syndrome (Hyper-IgE Syndrome)
11/2016 - 12/2009
2Pneumonia (Pneumonitis)
11/2022 - 01/2021
2COVID-19
04/2022 - 01/2021
2Autoimmune Hemolytic Anemia (Cold Agglutinin Disease)
01/2021 - 11/2017
2Lymphopenia (Lymphocytopenia)
01/2021 - 01/2016
2Neoplasms (Cancer)
01/2020 - 11/2017
2Diarrhea
11/2019 - 11/2017
2Cytopenia
11/2019 - 05/2017
2Eczema
11/2017 - 01/2016
2Reinfection
11/2017 - 11/2016
2Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
01/2016 - 12/2012
2Disease Susceptibility (Diathesis)
03/2015 - 10/2004
2Immediate Hypersensitivity
12/2014 - 07/2014
2Atopic Dermatitis (Atopic Eczema)
07/2010 - 12/2009
2Primary Immunodeficiency Diseases
01/2010 - 11/2008
1Sepsis (Septicemia)
11/2021
1Human Influenza (Influenza)
01/2021
1Genomic Instability
01/2020
1Chronic Granulomatous Disease
01/2019
1Chronic Mucocutaneous Candidiasis
01/2019
1Mycoses (Diseases, Fungus)
01/2018
1Hashimoto Disease (Thyroiditis, Hashimoto)
01/2018
1Ataxia Telangiectasia (Louis Bar Syndrome)
01/2018
1Porcine Reproductive and Respiratory Syndrome (PRRS)
01/2018
1Otitis
11/2017
1Angioedema
10/2016
1Urticaria (Hives)
10/2016
1Graft vs Host Disease (Graft-Versus-Host Disease)
01/2016
1Fibrosis (Cirrhosis)
01/2016
1Pulmonary Fibrosis (Fibrosing Alveolitis)
01/2016
1Wounds and Injuries (Trauma)
08/2015
1Respiratory Tract Infections (Respiratory Tract Infection)
08/2015

Drug/Important Bio-Agent (IBA)

13AllergensIBA
11/2022 - 10/2003
12Immunoglobulin E (IgE)IBA
01/2022 - 10/2003
8Interleukin-4 Receptors (Interleukin 4 Receptor)IBA
11/2022 - 10/2003
8CytokinesIBA
10/2016 - 10/2004
5Interleukin-4 (Interleukin 4)IBA
12/2020 - 10/2004
5Interleukin-13IBA
01/2016 - 10/2004
4AntigensIBA
01/2021 - 05/2010
4AntibodiesIBA
01/2021 - 03/2011
4STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
11/2020 - 08/2015
3Anti-Bacterial Agents (Antibiotics)IBA
01/2022 - 12/2016
3Particulate MatterIBA
11/2020 - 08/2015
3Nonsense Codon (Nonsense Mutation)IBA
01/2018 - 01/2015
3InterleukinsIBA
01/2016 - 10/2004
2Environmental Pollutants (Pollutants, Environmental)IBA
11/2022 - 11/2020
2AutoantigensIBA
05/2022 - 11/2005
2Immunoglobulins (Immunoglobulin)IBA
01/2022 - 11/2008
2ruxolitinibIBA
01/2021 - 05/2017
2Proteins (Proteins, Gene)FDA Link
01/2021 - 01/2018
2STAT1 Transcription FactorIBA
01/2019 - 01/2015
2Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA
10/2018 - 08/2015
2InterferonsIBA
05/2017 - 06/2015
2Transcription Factors (Transcription Factor)IBA
01/2016 - 07/2015
2OvalbuminIBA
12/2014 - 01/2013
2Immunoglobulin G (IgG)IBA
12/2014 - 03/2011
1beta CateninIBA
11/2022
1Notch ReceptorsIBA
04/2022
1Mechanistic Target of Rapamycin Complex 1IBA
04/2022
1Histone Deacetylases (Histone Deacetylase)IBA
11/2021
1Histone Deacetylase InhibitorsIBA
11/2021
1ZincIBA
11/2021
1RNA (Ribonucleic Acid)IBA
01/2021
1Epoprostenol (Prostacyclin)FDA LinkGeneric
01/2021
1Viral RNAIBA
01/2021
1AmphiregulinIBA
01/2021
1Transforming Growth Factor beta (TGF-beta)IBA
12/2020
1Notch4 ReceptorIBA
11/2020
1DNA-Directed DNA Polymerase (Polymerases, DNA)IBA
01/2020
1Abatacept (Orencia)FDA Link
11/2019
1Interleukin-6 Receptors (Interleukin 6 Receptor)IBA
05/2019
1NADPH Oxidases (NAD(P)H oxidase)IBA
01/2019
1Jagged-1 ProteinIBA
10/2018
1ThyroglobulinFDA Link
01/2018
1Pattern Recognition ReceptorsIBA
01/2018
1EndotoxinsIBA
01/2018
1Janus Kinase 1IBA
05/2017
1Epinephrine (Adrenaline)FDA LinkGeneric
01/2017
1Interleukin-2 (IL2)IBA
01/2016
1Bleomycin (Blenoxane)FDA LinkGeneric
01/2016
1Immunoglobulin A (IgA)IBA
08/2015
1Interleukin-17 (Interleukin 17)IBA
08/2015

Therapy/Procedure

11Therapeutics
01/2021 - 12/2005
9Immunotherapy
01/2017 - 06/2009
2Hematopoietic Stem Cell Transplantation
01/2022 - 01/2016
1Bridge Therapy
01/2021
1Diet Therapy (Therapy, Diet)
12/2016